West Indies were reduced to 31 for 4 by the ninth over.
Pakistan won the toss and elected to field. Imad Wasim ran through the West Indies top order yet again, bagging the wickets of Johnson Charles, Chadwick Walton and Dwayne Bravo.
Kesrick Williams struck twice in quick succession to dismiss the Pakistan openers on his debut.
Shoaib Malik (above) in company of Babar Azam put on an unbeaten half century stand for the third wicket and ensured Pakistan's easy win. The hosts won by eight wickets and sealed the three-match series 3-0.
Pakistan began their chase well, working the ball around gaps for singles and twos.
Marlon Samuels remained unbeaten till the end. However, he failed to score at over run a ball as West Indies were restricted to 103 for 5 in their 20 overs. Samuels hit only three boundaries in his 59-ball knock.